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I can reassure you that xanax and bupropion will not adversely effect each other. Xanax is not a long term solution, neither for anxiety or depression. To prevent symptoms sustainably, bupropion is a better option and can be try. Xanax would be reserved only when symptoms occurs and such situations should happened less frequently because of bupropion effectiveness.
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Sara Tremblay suggests meeting with your pharmacist.