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Polyendocrine metabolic ovarian syndrome

Published on 7 octobre 2026 at 4:00 / Updated on 21 octobre 2026 at 8:01

Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome (PCOS), is characterized by a set of symptoms related to a hormonal imbalance in women. These symptoms can appear as early as puberty and impact the appearance, reproductive health, and metabolism of those affected.

The name of the syndrome has been modified to better reflect how it disrupts metabolism and hormones. PMOS can occur as early as puberty and persist after menopause. Symptoms can vary from person to person and change over time. Symptoms include, among others:

  • Irregular periods
  • Acne
  • Excessive body or facial hair
  • Hair thinning or balding
  • Cysts on the ovaries

PMOS may also be associated with complications or other conditions, such as:

  • Difficulty conceiving or infertility
  • Pregnancy complications (e.g., preeclampsia, gestational diabetes)
  • Type 2 diabetes
  • Overweight or obesity
  • High blood pressure
  • High cholesterol levels
  • Increased risk of endometrial cancer

Causes and triggers

The exact cause of polyendocrine metabolic ovarian syndrome is unknown. Several factors may play a role, such as hormonal imbalances or genetic predisposition. People with a family history of PMOS or type 2 diabetes may be at greater risk.

Treatment

There is no cure for PMOS. The treatment rather aims to reduce the symptoms and the risk of certain associated health problems. It can vary according to age and whether the patient wishes to become pregnant. Here are some examples:

  • Medications to modify the effects of certain hormones
  • Medications to help regulate periods
  • Medications to improve the chances of getting pregnant

Healthy lifestyle habits, such as healthy eating and regular physical activity, can help reduce symptoms and the risk of certain related health problems.

When should I see a health care professional?

Consult your health care provider in the following cases:

  • Your periods are irregular or absent
  • You are gaining weight for no apparent reason
  • You have difficulty getting pregnant
  • You notice more hair on your face or body, or your hair becomes thinner or falls out

For more information:

  • YourPeriod.ca from the Society of Obstetricians and Gynaecologists of Canada
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