Salvia divinorum

Published on July 11, 2024 at 8:00 / Updated on July 25, 2024 at 8:00

Synonyms	The most common synonyms are: Maria pastora, Magic mint, Purple sticky, Sally D, Diviner's sage, Holy sage.
Classification	Hallucinogen: Causes users to see, hear or feel things that do not exist.
Visual description	Salvia divinorum is a plant that belongs to the mint family and is native to Mexico. Used in its plant form (fresh or dried leaves) or as a white powder.
Mechanism of action	Highly selective kappa opioid receptor agonist (KOR).
Routes of administration	Inhalation: (the most common) Dried leaves or an extract of salvinorin A (the main active ingredient) are smoked. Sublingual: The leaves are chewed and placed under the tongue.

Effects sought out by the user

Analgesia
Delirium
Distorted perceptions
Dysphoria
Out-of-body experiences

Sedation
Synesthesia (crossing of 2 or more senses)
Users become indifferent to their surroundings
Vivid hallucinations

Toxic effects
Mild intoxication	Moderate intoxication	Severe intoxication
Dizziness Nausea	Bradycardia Hallucinations Headache Incoordination Shivering Slurred speech Sweating Vertigo Vomiting	Anxiety Dysphoria Irresponsible behaviour Loss of short-term memory Unconsciousness

Effects associated with chronic use

Continuous exposure causes aversion, which deters users.

Addiction

Rarely observed.

Withdrawal

Headache, drowsiness.

Onset and duration of action
Route of administration	Onset of action	Duration of psychotropiceffect
Inhaled	< 30 seconds	5 to 10 minutes, then wears off after 20 to 30 minutes
Sublingual	5 to 10 minutes	1 hour then wears off after 1 hour

Intoxication management

No antidote available.
Treatment is mainly symptomatic.

Many different street drugs are sold under the same name. Furthermore, nothing guarantees the quantity, purity or even the content of a street drug in spite of the fact that it may, in some cases, look like medication.

If you need help or want to learn more:

Canadian Centre on Substance Use and Addiction

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