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Medication information

Orkambi 125+100mg granule pack

This medication is typically used for cystic fibrosis. It requires a few weeks to take effect.

Instructions

This medication is typically used twice a day. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Important: Follow the instructions on the label. Do not use more of this product, or more often, than prescribed.

It must be used regularly and continuously to maintain its beneficial effects. Be sure to keep an adequate supply on hand. This product must be used according to the instructions provided by your doctor or pharmacist. For more information, read the instructions in the package carefully.

If you remember missing a dose within 6 hours of the time it is usually taken, take the missed dose as soon as possible, then take the next dose at the regularly scheduled time. If the dose is missed by more than 6 hours, skip the missed dose. Do not double the next dose to catch up. This medication is more effective if taken with high-fat-containing foods. Always take it with a meal or a snack that contains such products.

Avoid grapefruit and grapefruit juice during your treatment. Grapefruit can seriously affect how this medication works.

Side effects

In addition to its desired action, this medication may cause some side effects, notably:

  • it may cause diarrhea;
  • it may cause difficulty breathing;
  • it may cause spots or redness of the skin;
  • it may cause unusual tiredness;
  • it may cause nausea or, rarely, vomiting;
  • it can affect the menstrual cycle.

Each person may react differently to a treatment. If you think this medication may be causing side effects (including those described here, or others), talk to your doctor or pharmacist. He or she can help you to determine whether or not the medication is the source of the problem.

Storage

As with most medications, this product should be stored at room temperature. Store it in a secure location where it will not be exposed to excessive heat, moisture or direct sunlight. Make sure that any leftover portion is disposed of safely.

Additional Information

Blood tests must be done regularly while using this medication. A blood test will indicate whether your treatment is having the desired effect. It will also provide the necessary information for adjusting the dosage to the lowest effective dose, thus decreasing the risk of side effects. Be sure to keep all your appointments.

This medication may interact with other medications or supplements, sometimes significantly. Many interactions, however, may be dealt with by a dosage adjustment or a change in medication schedule. Check with your pharmacist before using this medication in combination with any other medications (including non-prescription products), vitamins or natural products.

A treatment with this medication requires regular monitoring by a doctor. Be sure to see your doctor for all regularly scheduled appointments.

General notes

When meeting with any health professional, it is important for you to share the following information:

  • Your medical history and allergies (medication, food, or other);
  • If you smoke, are pregnant, are planning a pregnancy, or are breastfeeding;
  • The names of all the medications you take, whether you take them regularly or once in a while, including over-the-counter medications, vitamins, and natural health products.


It is also strongly recommended that you keep an up-to-date list of all the medications you take and carry it with you at all times. This could be useful if you have to see a health professional or need emergency care.

Keep all your medications out of the reach of children and pets and return any unused or expired medications to the pharmacy for proper disposal.