Major therapeutic interest

  • Treating skin lesions, moderately deep wounds, and first- and second-degree thermal burns (gel used topically);
  • Relieving occasional constipation (latex taken orally).

Other therapeutic interest / Traditional Use

  • Treating genital herpes (gel used topically);
  • Treating desquamation, erythema, and infiltration linked to psoriasis (gel used topically);
  • Reducing undesirable effects on skin caused by radiation therapy: erythema, desquamation, and itching (gel used topically);
  • Lowering blood glucose levels in diabetics (gel taken orally);
  • Treating hyperlipidemia (excess of LDL cholesterol and triglycerides in the blood) (gel taken orally).


Latex (taken orally):

  • Children under 12 years of age;
  • Pregnancy and breastfeeding;
  • Cardiac diseases;
  • Abdominal pains of unknown origin;
  • Heavy menstruation;
  • Intestinal obstruction, acute intestinal inflammation;
  • Diarrhea;
  • Chronic or severe constipation;
  • Hemorrhoids;
  • Ulcers;
  • Appendicitis;
  • Kidney disorders;
  • Varicose veins;
  • Long-term use (more than 8 to 10 days).

Gel (taken orally):

  • Diabetes: Use carefully, under close medical supervision with closely monitored blood glucose levels.

Important Notice

  • Although aloe gel is traditionally believed to reduce blood glucose levels when taken orally, no aloe products can replace conventional diabetes medication. Medication prescribed by a physician should never be replaced with an alternative remedy. Self-medication can cause serious problems. Diabetics using aloe as a supplement require strict glycemia monitoring;
  • Aloe gel should not be applied to severely infected wounds.

Drug Interactions

Known human interactions


  • Increases the hypoglycemic effect of Diabeta;

Suspected interactions

Latex (high doses or long-term use):

  • May increase potassium loss caused by diuretics (Hydrochlorothiazide, Lasix, Aldactone, etc.) and corticosteroids (Prednisone);
  • May increase the effect of Lanoxin;
  • May decrease the absorption of oral medications due to accelerated intestinal transit.


  • May increase effect of insulin and oral antidiabetics (Actos, Diamicron, Avandia, Glucophage, etc.), requiring dosage adjustments for diabetic patients.

Parts used

Latex (sap) and gel (from the leaves)

Main constituents

  • Latex: Anthracenic derivatives (anthraquinones, barboline, isobarboline, aloe-emodine, etc.), bitters;
  • Gel: Polysaccharides, pectins.
  • Note: The latex and gel act in different ways.

Other names

Aloe vera, Aloe barbadensis, Aloe capensis, Burn Plant