Major therapeutic interest
- Used as an additional treatment for angina pectoris, chest pain, congestive heart failure, cardiomyopathy, and high blood pressure;
- Reducing harmful effects of doxorubicin during cancer treatment (cardioprotective);
- Treating periodontitis (topical application).
Other therapeutic interest / Traditional Use
- Treating certain neurodegenerative illnesses like Parkinson’s and Huntington’s;
- Boosting the immune system (HIV/AIDS);
- Improving athletic performance;
- Used as an antioxidant (to neutralize the free radicals caused by pollution, poor diet, overmedication, and stress that can result in many problems, including circulatory and joint problems and skin ageing).
- Obstructed bile duct or severe liver disease.
- Self-medication can be dangerous. CoQ10 for heart problems or as a supplement during chemotherapy should only be taken under medical supervision.
Known human interactions
- Reduces effect of Coumadin;
- Some drugs cause a CoQ10 deficiency. These include anti-cholesterol drugs from the statin family (like Mevacoran, Lipitor, etc), beta blockers (like Inderal, Betaloc, etc.), antipsychotics in the phenothiazin family (like Fluphenazine , Largactil, etc.), tricyclic antidepressants (like Triavil, Norpramin, Tofranil, etc.), and certain anti-hypertensive drugs (like Hydrochlorothiazide, Catapres, Apresoline, etc.)
Ubiquinone, ubidecarenone, coenzyme Q