Major therapeutic interest
- Treating arthritis pain, especially back pain.
Other therapeutic interest / Traditional Use
- Stimulating the appetite;
- Treating a variety of digestive problems like bloating, nausea, and slow digestion.
- Gastric or duodenal ulcers;
- Breastfeeding: Safety has not yet been established;
- Cardiac disorder : Low and/or high blood pressure;
- Diabetes: Use carefully, with closely monitored blood glucose levels.
Known human interactions
- Increases the anticoagulant effect of Coumadin.
Known animal interactions
- Alters the action of antihypertensive drugs with possible interaction with drugs from different categories, including Hydrochlorothiazide, Inderal, Lopresor, Adalat, Cardizem (Dilitazem), Norvasc, Accupril, Altace, Capoten, Monopril, Vasotec, Cozaar, and others;
- Alters the effects of drugs that affect heart rate: possible interactions with Lanoxin and with anti-arrhythmic drugs like Inderal, Cordarone, Quinidine, etc.;
- Hypoglycemic effect in animals, with possible potentiation of the effects of insulin and oral antidiabetic drugs like Actos, Diabeta, Diamicron, Avandia, Glucophage, etc.
- May increase the effects of anticoagulants/antithrombotic agents (Coumadin, Lovenox, heparin, etc.), anti-platelet drugs (Plavix, Ticlid), and of salicylic acid derivatives (acetylsalicylic acid or ASA, aspirin, Entrophen, etc.) and other nonsteroidal anti-inflammatory drugs (NSAIDs) (Voltaren, Ibuprofen [Advil, Motrin], Naprosyn, etc.);
- May diminish the effects of antacids that act on gastric acid secretion and drugs used to treat acid reflux (Pepcid AC, Zantac, Losec, Pantoloc, Pariet, Prevacid, etc.)
- Iridoids (harpagoside, procumbide), flavonoids, beta-sitosterol.
Harpagophytum procumbens, Wood Spider