- Omega-6 type fatty acids: linoleic and gammalinoleic acid (LA, GLA)
Major therapeutic interest
- Relieving symptoms of PMS;
- Reducing breast pain associated with PMS (mastalgia);
- Treating osteoporosis: slows spinal column bone mass and bone mineral loss.
Other therapeutic interest / Traditional Use
- Treating autoimmune disorders, particularly multiple sclerosis;
- Treating eczema;
- Relieving symptoms of chronic inflammation due to rheumatoid arthritis;
- Slowing the progression of diabetic neuropathy;
- Treating attention deficit disorder and hyperactivity in children;
- Relieving menopause-related symptoms such as hot flashes and excessive sweating;
- Treating chronic fatigue syndrome.
- Epilepsy and seizure disorder: Lowers the epileptic threshold;
- Schizophrenia: May cause convulsions;
- Pregnancy: Safety for use during pregnancy has not yet been established.
- One case is reported in the literature of a patient who had an epileptic seizure under anesthesia after consuming evening primrose oil. However, the concomitant use of other drugs was also noted.
Known human interactions
- Increases the incidence of epileptic seizures when taken with anticonvulsants (Lamictal, Topamax, etc.);
- Increases the incidence of epileptic seizures when taken with antipsychotics (Fluanxol, Largactil, etc.)
- May heighten the effect of anticoagulant/antithrombotic drugs (Coumadin, Lovenox, heparin, etc.), antiplatelets (Plavix, Ticlid), as well as salicylic acid derivatives (acetylsalicylic acid or ASA, Aspirin, Entrophen, etc.) and other nonsteroidal anti-inflammatory drugs (NSAIDs) (Voltaren, Ibuprofen [Advil, Motrin], Naprosyn, etc.)
Fever plant, King’s cure-all